INTRAMUSCULAR INJECTION
Because Adequan® Canine (polysulfated glycosaminoglycan or PSGAG) is administered intramuscularly (IM), it gets to the joint and starts to work faster than oral treatments.
 

PSGAG binds to both albumin and chi-and beta-globulins. The extent of the binding is suggested to be 30 to 40 percent. Therefore, the drug may be present in both bound and free form in the bloodstream. Because of PSGAG’S relatively low molecular weight, the synovial membrane is not a significant barrier to distribution of PSGAG form the bloodstream to the synovial fluid. Distribution from the synovial fluid to the cartilage takes place by diffusion. In the articular cartilage the drug is deposited into the cartilage matrix.
 

Adequan® Canine is safe, generally well tolerated and unlikely to produce gastrointestinal upsets at the recommended dose.